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Symbol
Name
ID

Apc
APC, WNT signaling pathway regulator
MGI:88039

Phenotype annotations related to liver/biliary system

Darker colors indicate more annotations

Human Phenotypes	Hepatosplenomegaly	Micronodular cirrhosis	Subacute progressive viral hepatitis	Extrahepatic cholestasis	Jaundice	Neoplasm of the liver	Hepatoblastoma	Hepatocellular carcinoma
Disease(s) Associated with APC	Hepatosplenomegaly	Micronodular cirrhosis	Subacute progressive viral hepatitis	Extrahepatic cholestasis	Jaundice	Neoplasm of the liver	Hepatoblastoma	Hepatocellular carcinoma
familial adenomatous polyposis 1
hepatocellular carcinoma
pancreatic cancer

Mouse Phenotypes		enlarged liver	liver hyperplasia	liver inflammation	abnormal liver morphology	hepatic steatosis	increased liver tumor incidence	increased hepatocellular carcinoma incidence
Availability	Mouse Genotype	enlarged liver	liver hyperplasia	liver inflammation	abnormal liver morphology	hepatic steatosis	increased liver tumor incidence	increased hepatocellular carcinoma incidence
	Apc^tm1Tno/Apc^tm1Tno
	Apc^Min/Apc⁺
	Apc^tm1Rak/Apc⁺
	Apc^tm1Tno/Apc⁺
	Apc^tm2Rfo/Apc⁺
	Apc^tm2Tno/Apc⁺
	Apc^tm2.1Cip/Apc^tm2.1Cip (conditional)
	Apc^tm2.1Cip/Apc^tm2.1Cip Tg(Ttr-cre/Esr1*)1Vco/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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